Front Row lecture series
Sensing danger: How the nervous and immune systems coordinate inflammation
Alejandra Mendoza, PhD
Assistant Professor, Department of Immunology and Microbiology
Wednesday, November 5, 2025
4:00 p.m. PT | 7:00 p.m. ET
Just as we can distinguish between the sting of heat and the chill of cold, our immune system is finely tuned to recognize and respond to a wide range of threats, from viruses and bacteria to allergens and injury. This complex sensing relies on communication between diverse cell types, including sensory neurons and immune cells, to ensure responses are tailored to the specific challenge. In this free Front Row lecture, assistant professor Alejandra Mendoza explored how neuro-immune cellular circuits regulate inflammation, pain, and immunity. By bridging neuroscience and immunology, her research is revealing how our bodies interpret signals from the environment to guide immune decisions, from fighting infections to controlling tumor growth and chronic inflammatory diseases.
Presented: November 5, 2025
Presentation slides
Key Takeaways
Just as we can distinguish between the sting of heat and the chill of cold, our immune system is finely tuned to recognize and respond to a wide range of threats, from viruses and bacteria to allergens and injury. This complex sensing relies on communication between diverse cell types, including sensory neurons and immune cells, to ensure responses are tailored to the specific challenge. In this free Front Row lecture, assistant professor Alejandra Mendoza explored how neuro-immune cellular circuits regulate inflammation, pain, and immunity. By bridging neuroscience and immunology, her research is revealing how our bodies interpret signals from the environment to guide immune decisions, from fighting infections to controlling tumor growth and chronic inflammatory diseases.
Speaker Spotlight

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Scripps Research assistant professor awarded NIH HEAL Initiative grant
The National Institutes for Health’s (NIH) HEAL Initiative has awarded Alejandra Mendoza, PhD, assistant professor of Immunology and Microbiology, more than $1.6 million as part of a DP2 grant designed to support early-stage investigators with highly innovative and impactful research.
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Annual Mentoring Awards Announced
This year, the Award for Trainee Mentorship went to Rose Hill, a postdoctoral scholar in the lab of Professor Ardem Patapoutian, and the Outstanding Mentor Award went to Alejandra Mendoza, an assistant professor in the Department of Immunology and Microbiology.
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