Peering into the mitochondria to reveal cellular stress and disease

The mitochondria are well known for being cellular “powerhouses,” given their important role in energy generation. Yet, emerging research is now suggesting these organelles also play a key role as the stress-sensors for the cell. In this free Front Row lecture, Scripps Research assistant professor Danielle Grotjahn explored how mitochondria change shape in response to different genetic and environmental stressors. By harnessing cutting-edge imaging technologies to examine mitochondria in these never-before-seen-ways, Grotjahn is revealing how these organelles can predict overall cellular health and even disease, including neurodegenerative disorders and cancer.

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